M. Wink, Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective, Phytochemistry, vol.64, pp.3-19, 2003.

S. Lopez-legentil, N. Bontemps-subielos, X. Turon, and B. Banaigs, Secondary metabolite and inorganic contents in Cystodytes sp. (Ascidiacea): temporal patterns and association with reproduction and growth, Marine Biology, vol.151, pp.293-299, 2007.

M. A. Becerro, X. Turon, and M. J. Uriz, Multiple functions for secondary metabolites in encrusting marine invertebrates, Journal of Chemical Ecology, vol.23, pp.1527-1547, 1997.

G. Cronin, Resource allocation in seaweeds and marine invertebrates: chemical defense patterns in relation to defence theories, Marine Chemical Ecology, pp.325-353, 2001.

P. M. Dewick, Medicinal natural products: a biosynthetic approach, pp.7-34, 2002.

W. Takken and M. Dicke, Chemical ecology-A multidisciplinary approach, Chemical Ecology: From Gene to Ecosystem, vol.16, pp.1-8, 2006.

R. Coma and M. Ribes, Seasonal energetic constraints in Mediterranean benthic suspension feeders: effects at different levels of ecological organization, Oikos, vol.101, pp.205-215, 2003.

M. J. Uriz, X. Turon, M. A. Becerro, and J. Galera, Feeding deterrence in sponges. The role of toxicity, physical defenses, energetic contents, and life-history stage, Journal of Experimental Marine Biology and Ecology, vol.205, pp.187-204, 1996.

S. Lopez-legentil, N. Bontemps-subielos, X. Turon, and B. Banaigs, Temporal variation in the production of four secondary metabolites in a colonial ascidian, Journal of Chemical Ecology, vol.32, pp.2079-2084, 2006.

X. Turon, I. Tarjuelo, and M. J. Uriz, Growth dynamics and mortality of the encrusting sponge Crambe crambe (Poecilosclerida) in contrasting habitats: correlation with population structure and investment in defence, Functional Ecology, vol.12, pp.631-639, 1998.

M. J. Uriz, X. Turon, M. A. Becerro, J. Galera, and J. Lozano, Patterns of resourceallocation to somatic, defensive and reproductive functions in the Mediterranean encrusting sponge Crambe crambe, Marine Ecology Progress Series, vol.124, pp.159-170, 1995.

M. A. Becerro, R. W. Thacker, X. Turon, M. J. Uriz, and V. J. Paul, Biogeography of sponge chemical ecology: comparisons of tropical and temperate defenses, Oecologia, vol.135, pp.91-101, 2003.

R. Marti, A. Fontana, M. J. Uriz, and G. Cimino, Quantitative assessment of natural toxicity in sponges: Toxicity bioassay versus compound quantification, Journal of Chemical Ecology, vol.29, pp.1307-1318, 2003.

X. Turon, M. A. Becerro, M. J. Uriz, and J. Llopis, Small scale association measures in epibenthic communities as a clue for allelochemical interactions, Oecologia, vol.108, pp.351-360, 1996.

M. Page, L. West, P. Northcote, C. Battershill, and M. Kelly, Spatial and temporal variability of cytotoxic metabolites in populations of the New Zealand sponge Mycale hentscheli, Journal of Chemical Ecology, vol.31, pp.1161-1174, 2005.

D. A. Abdo, C. A. Motti, C. N. Battershill, and E. S. Harvey, Temperature and spatiotemporal variability of salicylihalamide A in the sponge Haliclona sp, Journal of Chemical Ecology, vol.33, pp.1635-1645, 2007.

R. Marti, M. J. Uriz, and X. Turon, Seasonal and spatial variation of species toxicity in Mediterranean seaweed communities: correlation to biotic and abiotic factors, Marine Ecology Progress Series, vol.282, pp.73-85, 2004.

C. Ferretti, S. Vacca, D. Ciucis, C. Marengo, B. Duckworth et al., Growth dynamics and bioactivity variation of the Mediterranean demosponges Agelas oroides (Agelasida, Agelasidae) and Petrosia ficiformis (Haplosclerida, Petrosiidae). Marine Ecology-an Evolutionary Perspective, vol.30, pp.327-336, 2009.

X. Turon, M. A. Becerro, and M. J. Uriz, Seasonal patterns of toxicity in benthic invertebrates: The encrusting sponge Crambe crambe (Poecilosclerida), Oikos, vol.75, pp.33-40, 1996.

M. A. Becerro, X. Turon, and M. J. Uriz, Natural variation of toxicity in encrusting sponge Crambe crambe (Schmidt) in relation to size and environment, Journal of Chemical Ecology, vol.21, pp.1931-1946, 1995.

M. A. Becerro, M. J. Uriz, and X. Turon, Chemically-mediated interactions in benthic organisms: the chemical ecology of Crambe crambe (Porifera, Poecilosclerida), Hydrobiologia, vol.355, pp.77-89, 1997.

H. M. Luter and A. R. Duckworth, Influence of size and spatial competition on the bioactivity of coral reef sponges, Biochemical Systematics and Ecology, vol.38, pp.146-153, 2010.

H. M. Luter, A. R. Duckworth, and C. Syms, Cytotoxic and anti-microbial activity of the sponge Iotrochota sp. as a function of size and spatial competitors, Marine Biology Research, vol.3, pp.312-318, 2007.

M. Maida, A. R. Carroll, and J. C. Coll, Variability of terpene content in the soft coral Sinularia flexibilis (Coelenterata, Octocoralia) and its ecological implications, Journal of Chemical Ecology, vol.19, pp.2285-2296, 1993.

C. D. Harvell, W. Fenical, V. Roussis, J. L. Ruesink, and C. C. Griggs, Local and geographic variation in the defensive chemistry of a West Indian gorgonian coral (Briareum asbestinum), Marine Ecology Progress Series, vol.93, pp.165-173, 1993.

X. Turon, R. Marti, and M. J. Uriz, Chemical bioactivity of sponges along an environmental gradient in a Mediterranean cave, Scientia Marina, vol.73, pp.387-397, 2009.

W. Leong and J. R. Pawlik, Evidence of a resource trade-off between growth and chemical defenses among Caribbean coral reef sponges, Marine Ecology Progress Series, vol.406, pp.71-78, 2010.

J. R. Pawlik, T. P. Henkel, S. E. Mcmurray, S. Lopez-legentil, and T. L. Loh, Patterns of sponge recruitment and growth on a shipwreck corroborate chemical defense resource trade-off, Marine Ecology-Progress Series, vol.368, pp.137-143, 2008.

M. R. Viant, Applications of metabolomics to the environmental sciences, Metabolomics, vol.5, pp.1-2, 2009.

J. G. Bundy, M. P. Davey, and M. R. Viant, Environmental metabolomics: a critical review and future perspectives, Metabolomics, vol.5, pp.3-21, 2009.

E. K. Prince and G. Pohnert, Searching for signals in the noise: metabolomics in chemical ecology, Analytical and Bioanalytical Chemistry, vol.396, pp.193-197, 2010.

D. Sipkema, M. Franssen, R. Osinga, J. Tramper, and R. H. Wijffels, Marine sponges as pharmacy, Marine Biotechnology, vol.7, pp.142-162, 2005.

M. Sara and J. Vacelet, E ´ cologie des Demosponges, pp.462-576, 1973.

J. Laborel and J. Vacelet, Les grottes sous-marines obscures en Méditerranée, Comptes Rendus de l'Académie des Sciences, vol.248, pp.2619-2621, 1959.

L. Laubier, Le Coralligène des Albères. Monographie biocénotique, 1966.

E. Ballesteros, Mediterranean coralligenous assemblages: A synthesis of present knowledge, Oceanography and Marine Biology-an Annual Review, vol.44, pp.123-130, 2006.

T. Pérez, J. Ivanisevic, M. Dubois, L. Pedel, and O. P. Thomas, Oscarella balibaloi, a new sponge species (Homoscleromorpha: Plakinidae) from the Western Mediterranean Sea: cytological description, reproductive cycle and ecology, Marine Ecology: An Evolutionary Perspective, vol.32, pp.174-187, 2011.

J. Ivanisevic, O. P. Thomas, C. Lejeusne, P. Chevaldonné, and T. Pérez, Metabolic fingerprinting as an indicator of biodiversity: towards understanding inter-specific relationships among Homoscleromorpha sponges, Metabolomics, vol.2, pp.289-305, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01801749

J. L. Botsford, A comparison of ecotoxicological tests, Atla-Alternatives to Laboratory Animals, vol.30, pp.539-550, 2002.

M. W. Taylor, P. J. Schupp, I. Dahllof, S. Kjelleberg, and P. D. Steinberg, Host specificity in marine sponge associated bacteria, and potential implications for marine microbial diversity, Environmental Microbiology, vol.6, pp.121-130, 2004.

N. S. Webster, M. W. Taylor, F. Behnam, S. Lucker, and T. Rattei, Deep sequencing reveals exceptional diversity and modes of transmission for bacterial sponge symbionts, Environmental Microbiology, vol.12, pp.2070-2082, 2010.

N. S. Webster, R. E. Cobb, R. Soo, S. L. Anthony, and C. N. Battershill, Bacterial Community Dynamics in the Marine Sponge Rhopaloeides odorabile Under In Situ and Ex Situ Cultivation, Marine Biotechnology, vol.13, pp.296-304, 2011.

N. S. Webster and M. W. Taylor, Marine sponges and their microbial symbionts: love and other relationships, Environmental Microbiology, 2011.

S. Schmitt, P. Tsai, J. Bell, J. Fromont, and M. Ilan, Assessing the complex sponge microbiota-core, variable and species-specific bacterial communities in marine sponges, International Society for Microbial Ecology Journal
URL : https://hal.archives-ouvertes.fr/hal-01766426

A. E. Vishnyakov and A. Ereskovsky, Bacterial symbionts as an additional cytological marker for identification of sponges without a skeleton, Marine Biology, vol.156, pp.1625-1632, 2009.

J. Ivanisevic, T. Perez, A. V. Ereskovsky, G. Barnathan, and O. P. Thomas, Lysophospholipids in the Mediterranean sponge Oscarella tuberculata: Seasonal variability and putative biological role, vol.37, pp.537-545, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01766088

R. Marti, M. J. Uriz, and X. Turon, Spatial and temporal variation of natural toxicity in cnidarians, bryozoans and tunicates in Mediterranean caves, Scientia Marina, vol.69, pp.485-492, 2005.

A. R. Duckworth, C. N. Battershill, and D. R. Schiel, Effects of depth and water flow on growth, survival and bioactivity of two temperate sponges cultured in different seasons, Aquaculture, vol.242, pp.237-250, 2004.

S. A. Dworjanyn, J. T. Wright, N. A. Paul, R. De-nys, and P. D. Steinberg, Cost of chemical defence in the red alga Delisea pulchra, Oikos, vol.113, pp.13-22, 2006.

R. Baldacconi, C. Nonnis-marzano, E. Gaino, and G. Corriero, Sexual reproduction, larval development and release in Spongia officinalis L. (Porifera, Demospongiae) from the Apulian coast, Marine Biology, vol.152, pp.969-979, 2007.

M. Mercurio, G. Corriero, and E. Gaino, A 3-year investigation of sexual reproduction in Geodia cydonium, Marine Biology, vol.151, pp.1491-1500, 1811.

S. Engel and J. R. Pawlik, Interactions among Florida sponges. I. Reef habitats, Marine Ecology-Progress Series, vol.303, pp.133-144, 2005.

J. Jackson and L. Buss, Allelopathy and spatial competition among coralreef invertebrates, Proceedings of the National Academy of Sciences of the United States of America, vol.72, pp.5160-5163, 1975.

M. Puyana, Chemical ecology of Caribbean sponges of the genus Aplysina, Dissertation Abstracts International Part B: Science and Engineering, vol.62, p.5576, 2002.

U. Hentschel, M. Schmid, M. Wagner, L. Fieseler, and C. Gernert, Isolation and phylogenetic analysis of bacteria with antimicrobial activities from the Mediterranean sponges Aplysina aerophoba and Aplysina cavernicola, FEMS Microbiology Ecology, vol.35, pp.305-312, 2001.

B. Weiss, R. Ebel, M. Elbrä-chter, M. Kirchner, and P. Proksch, Defense metabolites from the marine sponge Verongia aerophoba, Biochemical Systematics and Ecology, vol.24, pp.1-7, 1996.

J. E. Thompson, Exudation of biologically active metabolites in the sponge Aplysina fistularis.1. Biological evidence, Marine Biology, vol.88, pp.23-26, 1985.

R. W. Thacker, M. A. Becerro, W. A. Lumbang, and V. J. Paul, Allelopathic interactions between sponges on a tropical reef, Ecology, vol.79, pp.1740-1750, 1998.

D. S. Wishart, Current Progress in computational metabolomics, Briefings in Bioinformatics, vol.8, pp.279-293, 2007.

W. Müller, M. Klemt, N. L. Thakur, H. C. Schröder, and A. Aiello, Molecular/chemical ecology in sponges: evidence for an adaptive antibacterial response in Suberites domuncula, Marine Biology, vol.144, pp.19-29, 2004.

H. C. Steel, R. Cockeran, and R. Anderson, Platelet-activating factor and lysoPAF possess direct antimicrobial properties in vitro, Apmis, vol.110, pp.158-164, 2002.

R. C. Bolser and M. E. Hay, Are tropical plants better defended? Palatability and defenses of temperate vs tropical seaweeds, Ecology, vol.77, pp.2269-2286, 1996.

M. Zabala and E. Ballesteros, Surface-dependent strategies and energy flux in benthic marine communities or why corals do not exist in the Mediterranean, Scientia Marina, vol.53, pp.3-17, 1989.

U. Hentschel, J. Hopke, M. Horn, A. B. Friedrich, and M. Wagner, Molecular Evidence for a Uniform Microbial Community in Sponges from Different Oceans, Applied and Environmental Microbiology, vol.68, pp.4431-4440, 2002.

N. M. Mohamed, J. J. Enticknap, J. E. Lohr, S. M. Mcintosh, and R. T. Hill, Changes in bacterial communities of the marine sponge Mycale laxissima on transfer into aquaculture, Applied Environmental Microbiology, vol.74, pp.1209-1222, 2008.

A. B. Friedrich, I. Fischer, P. Proksch, J. Hacker, and U. Hentschel, Temporal variation of the microbial community associated with the Mediterranean sponge Aplysina aerophoba, FEMS Microbiology Ecology, vol.38, pp.105-113, 2001.

M. W. Taylor, P. J. Schupp, R. De-nys, S. Kjelleberg, and P. D. Steinberg, Biogeography of bacteria associated with the marine sponge Cymbastela concentrica, Environmental Microbiology, vol.7, pp.419-433, 2005.